How to Unwind Both Ends of Actin Filaments

Emory University graduate student Ekram Towsif and Professor Shashank Shekhar have uncovered groundbreaking insights into the dynamics of actin filaments and the multifunctional actin-binding protein cyclase-associated protein (CAP). Using cutting-edge biophysical techniques, including microfluidics-assisted TIRF microscopy and multispectral single-molecule imaging, their research reveals CAP’s previously unknown role as a processive depolymerase at the barbed ends … More How to Unwind Both Ends of Actin Filaments

Prof. Shashank Shekhar named “Cell Scientist to Watch”

Prof. Shashank Shekhar, an Assistant Professor of Physics, has been named a “Cell Scientist to Watch” by the Journal of Cell Science. As a community-focused journal, Journal of Cell Science is particularly keen to support the next generation of cell biologists. The interview series Cell Scientists to Watch features talented researchers who have recently set … More Prof. Shashank Shekhar named “Cell Scientist to Watch”

Doing Without Choosing: The Physics of Intrinsic Motivation

In a recent paper in PRX Life, Prof. Nemenman and collaborators explore intrinsic motivation — the ability of biological or artificial agents to learn new skills without an explicit reward. They introduce a new method that can compute a certain quantity, called empowerment, which has been proposed as a good proxy for intrinsic motivation. Empowerment maximizes … More Doing Without Choosing: The Physics of Intrinsic Motivation

Prof. Justin Burton selected as a Winship Professor and receives APS Fellowship

Associate Professor Justin Burton was recently recognized with 2 separate acheivements for his scholarly research and contributions to the physics community. First, he was chosen as a Winship Distinguished Research Professor. Winship professors are tenured faculty (generally associate professors showing stellar progress toward promotion to full professor, or recently promoted full professors on a steep upward … More Prof. Justin Burton selected as a Winship Professor and receives APS Fellowship

Squeezing light strikes gold in photonics

Excited carriers in noble metal nanostructures have recently attracted considerable attention for photocatalysis, optical detection, and photonic circuitry. However, most nanoarchitectures fail to yield highly energetic carriers, which are usually necessary for these applications. The main reason for this bottleneck is the inefficiency of intraband carrier absorption in metals, dictated by momentum conservation. Due to … More Squeezing light strikes gold in photonics

Polarizing forces in a topological material

Chern insulators are paradigmatic topological insulators known for exhibiting quantized Hall conductance even without a magnetic field. Due to their topological nature, electrons within these materials cannot be thought of as forming compact wave packets, known as Wannier functions, pivotal for defining polarization. Consequently, for decades, it has not been clear how to understand the … More Polarizing forces in a topological material

Battering the roadblocks of RNA transcription

RNA polymerases must transit through protein roadblocks to produce full-length transcripts. Building on preliminary work by Finzi lab alumni Yan Yan and Wenxuan Xu, graduate student Jin Qian recently used magnetic tweezers to discover that RNA polymerases can backtrack and ram into longer lived protein roadblocks to transit through them during transcription. He was helped in … More Battering the roadblocks of RNA transcription